There are 161 5-letter words starting with V in the ENABLE dictionary — 2% of all 8,636 words at this length. At 4 points, V is worth more than most tiles without being awkward enough to hold back for — it is generally better placed than saved.
The list divides into 7 groups by second letter, the largest being the 52 words with vi. Scanning the right group is faster than reading the whole list, which is why it is broken up below rather than run alphabetically.
If you know more than one letter, this page stops being the fast way to find it. Enter what you have in the unscrambler — the Contains, Starts with and Ends with filters combine, and setting both length fields to 5 narrows this list to the handful your letters actually allow.
All 161 words, by second letter
VA… (35)
vacua vagal vague vagus vails vairs vakil vales valet valid valor valse value valve vamps vanda vaned vanes vangs vapid vapor varas varia varix varna varus varve vasal vases vasts vasty vatic vatus vault vaunt