There are 1,286 4-letter words containing S in the ENABLE dictionary — 33% of all 3,903 words at this length. S is a one-point tile, so the value in this list is positional rather than numerical — which of these you can play depends far more on where it fits the board than on what it scores.
The S falls in the fourth position more often than any other, in 727 of them. 90 of them use the letter more than once — asks, asps, bass, boss among them, which is the case worth checking twice when a game has told you a letter is present but not how many times.
If you know more than one letter, this page stops being the fast way to find it. Enter what you have in the unscrambler — the Contains, Starts with and Ends with filters combine, and setting both length fields to 4 narrows this list to the handful your letters actually allow.
Where the S sits
S in the first position (353)
sabe sabs sack sacs sade sadi safe saga sage sago sags sagy said sail sain sake saki sale sall salp sals salt same samp sand sane sang sank sans saps sard sari sark sash sass sate sati saul save sawn saws says scab scad scag scam scan scar scat scop scot scow scry scud scum scup scut seal seam sear seas seat secs sect seed seek seel seem seen seep seer sees sego segs seif seis self sell sels seme semi send sene sent sept sera sere serf sers seta sets sett sewn sews sext sexy shad shag shah sham shat shaw shay shea shed shes shew shim shin ship shit shiv shmo shod shoe shog shoo shop shot show shri shul shun shut sial sibb sibs sice sick sics side sift sigh sign sike sild silk sill silo silt sima simp sims sine sing sinh sink sins sipe sips sire sirs site sith sits size sizy skag skas skat skee skeg skep skew skid skim skin skip skis skit skua slab slag slam slap slat slaw slay sled slew slid slim slip slit slob sloe slog slop slot slow slub slue slug slum slur slut smew smit smog smug smut snag snap snaw sned snib snip snit snob snog snot snow snub snug snye soak soap soar sobs sock soda sods sofa soft soil soja soke sola sold sole soli solo sols soma some sone song sons sook soon soot soph sops sora sorb sord sore sori sorn sort soth sots souk soul soup sour sous sown sows soya soys spae span spar spas spat spay spaz spec sped spew spic spik spin spit spiv spot spry spud spue spun spur sris stab stag star stat staw stay stem step stet stew stey stir stoa stob stop stow stub stud stum stun stye suba subs such suck sudd suds sued suer sues suet sugh suit sulk sulu sumo sump sums sung sunk sunn suns supe sups suqs sura surd sure surf suss swab swag swam swan swap swat sway swig swim swob swop swot swum sybo syce syke syli sync syne syph
S in the second position (20)
asci asea ashy asks asps eses espy isba isle isms osar oses ossa psis psst tsar tsks used user uses
S in the third position (186)
also ansa apse arse base bash bask bass bast best bise bisk bosh bosk boss bush busk buss bust busy casa case cash cask cast cess cist cosh coss cost cosy cusk cusp cuss cyst dash desk disc dish disk diss dose doss dost dusk dust ease east easy else erst fash fast fess fisc fish fist foss fuse fuss gash gasp gast gest gist gosh gush gust hash hasp hast hest hisn hiss hist hose host hush husk jess jest jism josh joss just kiss kist koss lase lash lass last less lest lisp list lose loss lost lush lust lyse mash mask mass mast mesa mesh mess mise miso miss mist mosk moss most muse mush musk muss must ness nest nisi nose nosh nosy oast oust owse pase pash pass past peso pest pish piso piss pose posh post posy push puss rase rash rasp resh rest rise risk rose rosy ruse rush rusk rust task tass test tosh toss tost tush tusk ursa vasa vase vast vest visa vise wash wasp wast west wise wish wisp wiss wist wost wuss xyst zest