There are 612 4-letter words containing U in the ENABLE dictionary — 16% of all 3,903 words at this length. U is a one-point tile and the bag holds a lot of them, so these words are less about scoring than about shape: they are what clears a vowel-heavy rack, and in a daily guessing game they are how you test a vowel you have not placed yet.
The U falls in the second position more often than any other, in 402 of them. 13 of them use the letter more than once — fugu, guru, juju, kudu among them, which is the case worth checking twice when a game has told you a letter is present but not how many times.
If you know more than one letter, this page stops being the fast way to find it. Enter what you have in the unscrambler — the Contains, Starts with and Ends with filters combine, and setting both length fields to 4 narrows this list to the handful your letters actually allow.
Where the U sits
U in the first position (37)
udos ughs ugly ukes ulan ulna ulus ulva umbo umps unai unau unbe unci unco unde undo undy unit unto upas upby updo upon urbs urds urea urge uric urns ursa urus used user uses utas uvea
U in the second position (402)
auks auld aunt aura auto bubo bubs buck buds buff bugs buhl buhr bulb bulk bull bumf bump bums bund bung bunk bunn buns bunt buoy bura burd burg burl burn burp burr burs bury bush busk buss bust busy bute buts butt buys buzz cube cubs cuds cued cues cuff cuif cuke cull culm cult cunt cups curb curd cure curf curl curn curr curs curt cusk cusp cuss cute cuts duad dual dubs duce duci duck duct dude duds duel dues duet duff dugs duit duke dull duly duma dumb dump dune dung dunk duns dunt duos dupe dups dura dure durn duro durr dusk dust duty euro fubs fuci fuck fuds fuel fugs fugu fuji full fume fumy fund funk funs furl furs fury fuse fuss futz fuze fuzz guan guar guck gude guff guid gulf gull gulp guls gums gunk guns guru gush gust guts guvs guys hubs huck hued hues huff huge hugs huic hula hulk hull hump hums hung hunh hunk huns hunt hurl hurt hush husk huts juba jube judo juga jugs juju juke jump junk jupe jura jury just jute juts kudo kudu kues kuru luau lube luce luck lude lues luff luge lugs lull lulu lump lums luna lune lung lunk lunt luny lure lurk lush lust lute lutz luvs luxe much muck muds muff mugg mugs mule mull mumm mump mums mumu muni muns muon mura mure murk murr muse mush musk muss must mute muts mutt nubs nude nuke null numb nuns nurd nurl nuts ouch ouds ouph ours oust outs ouzo pubs puce puck puds puff pugh pugs puja puke pula pule puli pull pulp puls puma pump puna pung punk puns punt puny pupa pups pure puri purl purr purs push puss puts putt putz quad quag quai quay quey quid quin quip quit quiz quod rube rubs ruby ruck rudd rude rued ruer rues ruff ruga rugs ruin rule ruly rump rums rune rung runs runt ruse rush rusk rust ruth ruts suba subs such suck sudd suds sued suer sues suet sugh suit sulk sulu sumo sump sums sung sunk sunn suns supe sups suqs sura surd sure surf suss tuba tube tubs tuck tufa tuff tuft tugs tuis tule tump tuna tune tung tuns tups turd turf turk turn tush tusk tuts tutu vugg vugh vugs wuss yuan yuca yuch yuck yuga yuks yule yups yurt
U in the third position (150)
abut ague alum amus anus aqua arum baud bhut blub blue blur bout brut caul chub chug chum club clue coup crud crus crux daub daut doum dour doux drub drug drum eaux ecus emus etui faun faux feud feus flub flue flus flux foul four frug gaud gaum gaun gaur geum glue glug glum glut gnus gout grub grue grum haul haut hour jauk jaup jeux jouk knur laud leud loud loup lour lout maud maul maun maut moue neuk neum noun nous onus opus ovum pfui phut plug plum plus pouf pour pout rhus roue roup rout roux saul scud scum scup scut shul shun shut skua slub slue slug slum slur slut smug smut snub snug souk soul soup sour sous spud spue spun spur stub stud stum stun swum taus taut thud thug thus tour tout true trug vaus wauk waul waur yaud yaup yeuk your
U in the fourth position (23)
babu beau bedu ecru emeu genu habu iglu jehu kagu leku lieu litu menu meou prau tabu thou thru tofu tolu vatu zebu