There are 233 4-letter words starting with D in the ENABLE dictionary — 6% of all 3,903 words at this length. D is a one-point tile, so the value in this list is positional rather than numerical — which of these you can play depends far more on where it fits the board than on what it scores.
The list divides into 9 groups by second letter, the largest being the 51 words with do. Scanning the right group is faster than reading the whole list, which is why it is broken up below rather than run alphabetically.
If you know more than one letter, this page stops being the fast way to find it. Enter what you have in the unscrambler — the Contains, Starts with and Ends with filters combine, and setting both length fields to 4 narrows this list to the handful your letters actually allow.
All 233 words, by second letter
DA… (40)
dabs dace dada dado dads daff daft dago dags dahl dahs dais daks dale dals dame damn damp dams dang dank daps darb dare dark darn dart dash data date dato daub daut davy dawk dawn daws dawt days daze
DE… (41)
dead deaf deal dean dear debs debt deck deco deed deem deep deer dees deet defi deft defy deil deke dele delf deli dell dels deme demo demy dene dens dent deny dere derm desk deva devs dews dewy dexy deys
DH… (3)
dhak dhal dhow
DI… (37)
dial dibs dice dick dido didy died diel dies diet digs dike dill dime dims dine ding dink dins dint diol dips dipt dire dirk dirl dirt disc dish disk diss dita dite dits ditz diva dive
DJ… (1)
djin
DO… (51)
doat doby dock docs dodo doer does doff doge dogs dogy doit dojo dole doll dols dolt dome doms dona done dong dons doom door dopa dope dopy dore dork dorm dorp dorr dors dory dose doss dost dote doth dots doty doum dour doux dove down dows doxy doze dozy
DR… (17)
drab drag dram drat draw dray dree dreg drek drew drib drip drop drub drug drum drys
DU… (37)
duad dual dubs duce duci duck duct dude duds duel dues duet duff dugs duit duke dull duly duma dumb dump dune dung dunk duns dunt duos dupe dups dura dure durn duro durr dusk dust duty